CFAs: Antimicrobial Stewardship in the Sub-Saharan African Region

CFAs: Antimicrobial Stewardship in the Sub-Saharan African Region

Section

Deadline Date
October 4, 2025
Donor Agency
Pfizer
Grant Size
$10,000 to $100,000

Entries are now open for Antimicrobial Stewardship (AMS), one of the strategic objectives of the WHO Global Action Plan on AMR, aiming to promote the appropriate use of antimicrobials to optimize patient outcomes and reduce resistance development.

The main objectives of the Expert Roundtable were to identify gaps and challenges in properly deploying antibiotic therapies in Africa and AMR including regulatory and systemic challenges, challenges in patient care, the future of antibiotics R&D in Africa and to further explore on the role of small-molecule therapeutics in combating AMR.

Areas of Interests
  • The expectation is that proposed projects will identify and examine an AMR stewardship intervention/strategy that has the potential to:
    • Strengthening AMS practices in healthcare and community settings;
    • Reinforce regulatory bodies and health systems to develop centralized AMS support structures;
    • Improving access to and rational use of new and existing antibiotics;
    • Enhancing AMR surveillance and data sharing systems;
    • Advancing diagnostic technologies to support evidence-based treatment decisions;
    • Reinforcing AMR Research and Development (R&D) and Innovation;
    • Identifying and addressing gaps in clinical practice guidelines;
    • Promoting sustainable models for antibiotic production, supply, and delivery;
    • Developing standardized metrics to evaluate the effectiveness of AMS interventions;
    • Promote co-creation models between patients and healthcare providers to raise awareness about AMR, targeting rural and underserved populations.
Challenges 
  • In partnership with Pfizer, ISID invites organizations and individuals with a focus on AMR in & on the African continent to submit a grant proposal for consideration. Proposals that align with one or more of the following strategic objectives will be prioritized and can be considered a pilot proposal for future extensive work, where applicable:
    • Strengthening AMS practices in healthcare and community settings;
    • Reinforce regulatory bodies and health systems to develop centralized AMS support structures;
    • Improving access to and rational use of new and existing antibiotics;
    • Enhancing AMR surveillance and data sharing systems;
    • Advancing diagnostic technologies to support evidence-based treatment decisions;
    • Reinforcing AMR Research and Development (R&D) and Innovation;
    • Identifying and addressing gaps in clinical practice guidelines;
    • Promoting sustainable models for antibiotic production, supply, and delivery;
    • Developing standardized metrics to evaluate the effectiveness of AMS interventions;
    • Promote co-creation models between patients and healthcare providers to raise awareness about AMR, targeting rural and underserved populations.
Funding Information 
  • Individual projects requesting up to $100,000 US dollars will be considered. The total available budget related to this RFP is $400,000 US dollars to be shared between 4-6 recipients for a duration of 2 years.
Target Audience
  • The target audience for the AMS projects is broad and multidisciplinary, reflecting the complexity of the AMR challenge. While the aim is to ensure a coordinated, cross-sectoral approach to AMR, key stakeholders include healthcare professionals, public health authorities, policymakers, academic/research institutions, hospital/healthcare administrators, regulatory agencies, medicines authorities, community health workers, and the general public.
Eligibility Criteria 
  • Geographic Scope:
    • The applicant/entity must be based in Sub-Saharan Africa, with activities conducted at the regional, sub-regional, or national level. Initiatives operating within any of these geographic scopes across the African continent are eligible. Other regions of the world will not be considered.
  • Applicant Eligibility Criteria:
    • Eligibility is limited to organizations, institutions, or individuals residing and working within the Sub- Saharan African region.
    • Eligible applicants may include academic and research institutions, intergovernmental organizations, regional economic communities, scientific associations or societies, non-governmental organizations (NGOs), and other entities with a demonstrated commitment to AMR, all based or have a strong experience and/or previous partnerships within the Sub-Saharan African region.
    • Collaboration is strongly encouraged. Preference will be given to proposals that incorporate meaningful partnerships with relevant entities such as universities, hospitals, healthcare systems, public health institutions, or professional societies. These partners should have missions aligned with combating AMR, improving healthcare outcomes, or advancing public health goals.
    • Both intra-institutional collaborations (e.g., between departments or professional disciplines) and inter-institutional partnerships (e.g., across organizations, sectors, or borders) are encouraged. All partners must have All a clearly defined and relevant role, and the lead applicant must play a central role in the design and implementation of the proposed project.
    • Grass-roots, local organizations with proven track records are encouraged to apply. Initiatives targeting and uplifting vulnerable populations within the Sub-Saharan African continent will be prioritized.

For more information, visit Pfizer.

https://cdn.pfizer.com/pfizercom/2025-08/2025-I%26I-Sub-Saharan-Africa-AntimicrobialStewardship-QI.pdf?VersionId=aLTnqWo6hVKqh0.cm1X4yLNoH8LQSHyp

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